tag:blogger.com,1999:blog-5574479.post1913837961030203454..comments2024-03-29T06:53:23.405+00:00Comments on The IPKat: BGH: does an explanation make an invention?Verónica RodrÃguez Arguijohttp://www.blogger.com/profile/05763207846940036921noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-5574479.post-2933919325229087382011-08-26T14:16:38.268+01:002011-08-26T14:16:38.268+01:00This makes perfect sense. If the only contribution...This makes perfect sense. If the only contribution is finding out how the compound exerts its known effects, then this does not render a known teaching novel.<br /><br />However, the understanding of how the compound exerts its effect can then be applied in designing analogues (alternative compounds of similar chemical structure and having the same biological effect). For example, if it is discovered that a known anti-dememtia compound works by interacting with and stimulating or inhibiting a particular biological target (such as an enzyme, receptor or control element) then designing new analogue compounds based on that lead compound, but at the same time directed to interacting to that newly uncovered mechanism, may well represent an invention.Anonymousnoreply@blogger.com